Looking for the best contact cleaning solutions to keep your lenses fresh and your eyes comfortable? Discover personalized care systems that match your lenses and lifestyle, ensuring crystal-clear vision and all-day ease with every wear.
Your contacts should feel as fresh as the moment you put them in. That’s why finding the right cleaning solution matters every single day. Crystal-clear vision, lasting comfort, and real protection aren’t luxuries—they’re essentials for healthy eyes.
Millions of wearers trust hydrogen peroxide systems like Clear Care Plus to dissolve protein buildup overnight, waking up to lenses that feel new. Others rely on multi-purpose solutions such as Opti-Free Puremoist and Biotrue for their hydration-locking technology, keeping dryness at bay from morning to night. These aren’t just bottles—they’re daily rituals that make a tangible difference.
Struggling with gritty lenses or midday dryness? You’re not alone. Many users share how switching to a proven solution transformed irritation into all-day ease. RGP wearers found clarity with Boston Advance, while silicone hydrogel users praise Opti-Free’s reliability. One wearer put it simply: “My eyes stopped stinging the first night I used Clear Care. It was like seeing in HD again.” These real wins show the right solution truly earns its place in your routine.
Let’s match your lenses—and your lifestyle—with the perfect care system. Read on to discover exactly which formula works best for you.
List of Top 10 Contact Cleaning Solutions
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Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2 |
Clear Care Plus is perfect for contact lens wearers who crave crisp, fresh lenses without the dryness or irritation. If you hate that gritty feeling at the end of the day, this solution’s bubbling power lifts dirt and protein buildup like nothing else. The HydraGlyde Moisture Matrix locks in comfort, so your lenses feel silky all day long—ideal if your eyes get red or tired easily. Plus, it safely handles soft and rigid gas permeable lenses, making it a smart choice for anyone serious about clean, healthy vision. Just follow the steps—never skip—and enjoy the confidence of truly fresh lenses. |
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Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz |
Clear Care Plus is perfect for anyone who wears soft contact lenses, including silicone hydrogel and rigid gas permeable lenses. It’s great for daily use, offering deep cleaning and long-lasting moisture for a fresh lens feeling. |
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Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz |
This product is perfect for people who wear rigid gas permeable (RGP) lenses, including scleral, ortho-k, or standard RGP lenses. It’s ideal for those seeking a trusted, advanced cleaning solution that removes debris and deposits to keep lenses clean, comfortable, and safe—recommended by eye doctors for top-tier lens care. |
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Opti-Free Puremoist Multi-Purpose Contact Lens Cleaning and Disinfecting Solution with Lens Case, 10 FL Oz (Pack of 1) |
Perfect for contact lens wearers who want all-day comfort and clean, disinfected lenses. Opti-Free Puremoist uses HydraGlyde Moisture Matrix to keep lenses moist, reduce debris, and remove protein deposits. It kills harmful microorganisms, works on Silicone Hydrogel and Soft Lenses, and ensures fresh, comfortable wear from morning to night. |
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Clear Care Plus Cleaning Solution Travel Pack, No Flavor, 3 Fl Oz |
Clear Care Plus is perfect for contact lens users who want gentle yet effective cleaning and long-lasting moisture. Its hydrogen peroxide formula removes dirt and protein, while the HydraGlyde Moisture Matrix keeps lenses fresh. The platinum disc case safely neutralizes solution, making it ideal for all soft and rigid gas permeable lenses. |
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Opti-Free Puremoist Multi-Purpose Contact Lens Cleaning and Disinfecting Solution with Lens Case, 2 Fl Oz (Pack of 1) |
Opti-Free PureMoist is perfect for contact lens wearers who want all-day comfort and clean, disinfected lenses. Its exclusive formula kills microorganisms and HydraGlyde Moisture Matrix keeps lenses moist and clear of debris, ideal for silicone hydrogel or soft lenses. |
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Biotrue Contact Solution, Multi-Purpose Lens Solution for Soft Lenses, Cleans, Disinfects, Removes Protein Build-Up, Dirt & Debris, Hydrates, Stores & Conditions Contacts, 4 Fl Oz (Pack of 1) |
Biotrue Contact Solution is perfect for soft contact lens wearers who want clean, comfortable lenses all day. If your eyes feel dry or irritated after hours of screen time, or you notice blurry spots from protein buildup, this solution works like nature intended. It gently cleans, disinfects thoroughly, and locks in moisture—just like your own tears. With 20 hours of hydration and a formula that matches your eye’s natural pH, it keeps lenses feeling fresh whether you're on your phone, at work, or out all day. Ideal for daily lens storage, deep cleaning, and silicone hydrogel lenses too. Put comfort first—without the fuss. |
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Opti-free Puremoist Multi-Purpose Contact Lens Cleaning and Disinfecting Solution, 4 Fl Oz |
Opti-Free Puremoist is perfect for contact lens wearers who want all-day comfort and clean, safe lenses. It works great for Silicone Hydrogel or soft lenses, keeping eyes fresh and protected with its moisture cushion and germ-fighting power. |
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Bausch + Lomb Sensitive Eyes Saline Solution, Gentle Daily Rinse for Soft & Gas Permeable Contact Lenses, with Potassium, 12 Fl Oz (Pack of 2) |
This saline solution is perfect for contact lens wearers who want a gentle, daily rinse. It’s safe and easy to use, keeping your lenses clean and comfortable. |
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Renu Contact Lens Solution, Advanced Formula, Multi-Purpose Solution with Lens Case, Gently Cleans, Disinfects, Moisturizes & Hydrates Soft Lenses for All-Day Comfort, 12 Fl Oz (Pack of 2) |
Renu Contact Lens Solution is perfect for soft contact lens wearers who want all-day comfort and long-lasting moisture. It gently cleans, disinfects, and hydrates lenses, keeping eyes fresh and reducing dryness for up to 20 hours. |
Detailed Reviews
Discover the top 10 contact lens solutions trusted by experts and users for safety, comfort, and value.
Each one is reviewed for cleaning power, hydration, and ease of use.
Find your perfect match—whether you need gentle care for sensitive eyes or deep-cleaning travel sizes.
Get crystal-clear comfort daily with solutions proven to keep lenses fresh and eyes healthy.
1. Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2
Breathe crystal-clear comfort with every wear. Clear Care Plus uses bubbling hydrogen peroxide to deep clean your lenses and HydraGlyde Moisture Matrix to lock in lasting hydration—no more dryness or buildup.
Just soak overnight. The platinum disc in the case activates gentle cleaning. Safe for soft and RGP lenses. Always follow the full instructions—never apply solution directly to eyes.
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Perfect For:
Clear Care Plus is perfect for contact lens wearers who crave crisp, fresh lenses without the dryness or irritation. If you hate that gritty feeling at the end of the day, this solution’s bubbling power lifts dirt and protein buildup like nothing else. The HydraGlyde Moisture Matrix locks in comfort, so your lenses feel silky all day long—ideal if your eyes get red or tired easily. Plus, it safely handles soft and rigid gas permeable lenses, making it a smart choice for anyone serious about clean, healthy vision. Just follow the steps—never skip—and enjoy the confidence of truly fresh lenses.
Ready to Purchase?
2. Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz
Feel fresh lenses all day with Clear Care Plus. Its powerful hydrogen peroxide cleaning bubbles away dirt and protein buildup like nothing else. You get crystal-clear vision and unmatched comfort from morning till night.
Triple Action Cleaning loosens debris, deep cleans, and removes stubborn protein. The patented HydraGlyde Moisture Matrix locks in long-lasting hydration, so your soft lenses feel new every time.
Just place lenses in the case with Clear Care Plus Solution and wait at least 6 hours. The platinum disc neutralizes peroxide into a gentle saline—never touch the solution directly. Safe for all soft contacts, even silicone hydrogel and RGP lenses. Fresh, clean, comfortable eyes made simple.
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Perfect For:
Clear Care Plus is perfect for anyone who wears soft contact lenses, including silicone hydrogel and rigid gas permeable lenses. It’s great for daily use, offering deep cleaning and long-lasting moisture for a fresh lens feeling.
Ready to Purchase?
3. Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz
Step 1 in the Boston ADVANCE Formula Care System delivers deep cleaning for Rigid Gas Permeable lenses. Its advanced formula lifts debris and deposits quickly, while the tinted solution makes rinsing fast and thorough.
Trusted by eye doctors nationwide, Boston is the #1 recommended brand for RGP care. Bausch + Lomb’s eye experts created it to keep lenses clean, comfortable, and safe every day.
Perfect for scleral, ortho-k, and all RGP lenses.
Just 1 fl oz – powerful yet economical.
See clearer, feel fresher, wear with confidence.
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Perfect For:
This product is perfect for people who wear rigid gas permeable (RGP) lenses, including scleral, ortho-k, or standard RGP lenses. It’s ideal for those seeking a trusted, advanced cleaning solution that removes debris and deposits to keep lenses clean, comfortable, and safe—recommended by eye doctors for top-tier lens care.
Ready to Purchase?
4. Opti-Free Puremoist Multi-Purpose Contact Lens Cleaning and Disinfecting Solution with Lens Case, 10 FL Oz (Pack of 1)
Doctor-recommended protection meets all-day comfort. Opti-Free Puremoist is the trusted multi-purpose solution that cleans, disinfects, and keeps your lenses feeling fresh from morning to night.
Its exclusive formula destroys harmful microorganisms that can lead to eye infections. Meanwhile, HydraGlyde Moisture Matrix wraps your lenses in a cushion of hydration and blocks irritants like debris and protein buildup.
Your lenses stay smooth and comfortable. You see clearly without irritation. Simply clean, store, and go—every single day.
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Perfect For:
Perfect for contact lens wearers who want all-day comfort and clean, disinfected lenses. Opti-Free Puremoist uses HydraGlyde Moisture Matrix to keep lenses moist, reduce debris, and remove protein deposits. It kills harmful microorganisms, works on Silicone Hydrogel and Soft Lenses, and ensures fresh, comfortable wear from morning to night.
Ready to Purchase?
5. Clear Care Plus Cleaning Solution Travel Pack, No Flavor, 3 Fl Oz
Clear Care Plus Cleaning Solution is a travel-friendly pack for contact lenses. It uses hydrogen peroxide to clean and disinfect. The 3 Fl Oz size is perfect for on-the-go.
It keeps lenses moist and fresh with HydraGlyde technology. The triple-action formula removes dirt and protein easily.
The special lens case includes a platinum disc. It activates bubbling and turns the solution into a gentle saline. Safe for all soft and rigid gas permeable lenses.
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Perfect For:
Clear Care Plus is perfect for contact lens users who want gentle yet effective cleaning and long-lasting moisture. Its hydrogen peroxide formula removes dirt and protein, while the HydraGlyde Moisture Matrix keeps lenses fresh. The platinum disc case safely neutralizes solution, making it ideal for all soft and rigid gas permeable lenses.
Ready to Purchase?
6. Opti-Free Puremoist Multi-Purpose Contact Lens Cleaning and Disinfecting Solution with Lens Case, 2 Fl Oz (Pack of 1)
Doctor-recommended. All-day comfort. Total protection.
Opti-Free Puremoist is the #1 choice eye doctors make for cleaning and disinfecting soft lenses. It locks in moisture so your eyes feel fresh from morning to night. And it kills harmful germs that can cause infections.
HydraGlyde Moisture Matrix wraps your lenses in soothing cushion. Dirt and debris slide right off, keeping your vision clear. No more dryness even after hours of wear.
Safe and effective for silicone hydrogel and all soft lenses. Trust Opti-Free Puremoist to care for your eyes every single day.
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Perfect For:
Opti-Free PureMoist is perfect for contact lens wearers who want all-day comfort and clean, disinfected lenses. Its exclusive formula kills microorganisms and HydraGlyde Moisture Matrix keeps lenses moist and clear of debris, ideal for silicone hydrogel or soft lenses.
Ready to Purchase?
7. Biotrue Contact Solution, Multi-Purpose Lens Solution for Soft Lenses, Cleans, Disinfects, Removes Protein Build-Up, Dirt & Debris, Hydrates, Stores & Conditions Contacts, 4 Fl Oz (Pack of 1)
See clearly. Feel fresh. Biotrue Multi-Purpose Contact Solution cleans, disinfects, and removes protein build-up, dirt, and debris from your soft lenses. It's designed to match your eye’s natural biology for healthier, more comfortable wear.
Inspired by your eyes. This solution contains hyaluronan—a natural moisturizer found in tears—and matches the pH of healthy tears. It hydrates for up to 20 hours, keeping lenses moist even during screen time.
Store, rinse, or disinfect with one bottle. For soft and silicone hydrogel lenses. Trusted comfort, every day.
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Perfect For:
Biotrue Contact Solution is perfect for soft contact lens wearers who want clean, comfortable lenses all day. If your eyes feel dry or irritated after hours of screen time, or you notice blurry spots from protein buildup, this solution works like nature intended. It gently cleans, disinfects thoroughly, and locks in moisture—just like your own tears. With 20 hours of hydration and a formula that matches your eye’s natural pH, it keeps lenses feeling fresh whether you're on your phone, at work, or out all day. Ideal for daily lens storage, deep cleaning, and silicone hydrogel lenses too. Put comfort first—without the fuss.
Ready to Purchase?
8. Opti-free Puremoist Multi-Purpose Contact Lens Cleaning and Disinfecting Solution, 4 Fl Oz
Doctor-recommended. Opti-Free Puremoist is the trusted multi-purpose solution eye care professionals suggest most.
All-day comfort, guaranteed. No matter how busy your day gets, your lenses stay fresh and comfortable.
Kills infection-causing germs. Its exclusive formula eliminates harmful microorganisms for safer eyes.
HydraGlyde Moisture Matrix wraps your lenses in soothing hydration, blocking dirt and deposits. Works perfectly with all soft and silicone hydrogel lenses—cleaning, rinsing, and disinfecting in one simple step.
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Perfect For:
Opti-Free Puremoist is perfect for contact lens wearers who want all-day comfort and clean, safe lenses. It works great for Silicone Hydrogel or soft lenses, keeping eyes fresh and protected with its moisture cushion and germ-fighting power.
Ready to Purchase?
9. Bausch + Lomb Sensitive Eyes Saline Solution, Gentle Daily Rinse for Soft & Gas Permeable Contact Lenses, with Potassium, 12 Fl Oz (Pack of 2)
Bausch + Lomb Sensitive Eyes Saline Solution is a gentle daily rinse for soft and gas permeable contact lenses. It helps rinse lenses before insertion or after cleaning and includes potassium to support eye comfort.
This solution is safe for rinsing before or after heat, chemical, or hydrogen peroxide disinfection. Use it to dilute enzymatic cleaning tablets or store soft lenses after thermal disinfection. It’s made for easy, reliable care with minimal steps.
Bausch + Lomb has made trusted eye care products for over 150 years. Their line includes contact lens solutions, eye drops, vitamins, and ointments. These products aim to keep eyes moisturized, protected, and healthy every day.
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Perfect For:
This saline solution is perfect for contact lens wearers who want a gentle, daily rinse. It’s safe and easy to use, keeping your lenses clean and comfortable.
Ready to Purchase?
10. Renu Contact Lens Solution, Advanced Formula, Multi-Purpose Solution with Lens Case, Gently Cleans, Disinfects, Moisturizes & Hydrates Soft Lenses for All-Day Comfort, 12 Fl Oz (Pack of 2)
Renu Contact Lens Solution is made by Bausch + Lomb, a trusted name in eye care. It comes with a free lens case and is used by over 1 million households.
Keeps lenses hydrated for up to 20 hours. Gently cleans and disinfects daily. Prevents dryness and buildup on soft lenses.
This multi-purpose solution works fast to clean, disinfect, and moisturize. It’s safe for silicone hydrogel lenses and supports all-day comfort.
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Perfect For:
Renu Contact Lens Solution is perfect for soft contact lens wearers who want all-day comfort and long-lasting moisture. It gently cleans, disinfects, and hydrates lenses, keeping eyes fresh and reducing dryness for up to 20 hours.
Ready to Purchase?
Buying Guide
Fresh lenses, fresh eyes. The right solution keeps your contacts clean, comfy, and clear. Real users swear by formulas that fight dryness, remove gunk, and match their lens type.
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Lens Type Compatibility:
Soft, silicone hydrogel, or RGP lenses need tailored care. Hydrogen peroxide systems like Clear Care Plus work for all, while Boston Advance targets RGP lenses. Always check labels to avoid damage. -
Hydration Power:
Dry eyes? Prioritize solutions with HydraGlyde or hyaluronan. Opti-Free Puremoist and Biotrue lock in moisture for up to 20 hours. These ingredients mimic natural tears for lasting comfort. -
Protein Removal:
Daily wear leaves buildup. Hydrogen peroxide systems bubble away proteins overnight. Multi-purpose solutions like Biotrue clean and disinfect in one step. RGP users love Boston Advance for lifting stubborn debris. -
Travel-Friendly Options:
On-the-go? Grab Clear Care Plus Travel Pack (3 fl oz) or Opti-Free mini sizes. Compact bottles fit in bags without spills. Keep lenses fresh during commutes or trips. -
Safety & Neutralization:
Hydrogen peroxide must neutralize before lens insertion. Clear Care Plus uses a platinum disc to turn solution into saline in 6 hours. Never skip this step—it stings! Multi-purpose solutions skip this hassle. -
Trusted Brands Matter:
Eye doctors recommend Opti-Free, Bausch + Lomb, and Boston for reliability. Long-term brands invest in research, like HydraGlyde Moisture Matrix or Renu’s 20-hour hydration. Trust proven results.